This case demonstrates that cryoglobulinemic vasculitis can cause reversible parkinsonism and leukoencephalopathy that mimics neurodegenerative disease, responding dramatically to immunosuppression. The patient had type III mixed cryoglobulinemia without typical triggers (hepatitis C or monoclonal gammopathy), presenting with tremor, rigidity, cognitive decline, and extensive white matter changes. Read more 01 Mar 2026 - less than 1 minute read
This comprehensive review covers mucormycosis, a rapidly progressive invasive fungal infection with high neurological morbidity, particularly in the rhinocerebral form that can invade brain parenchyma. Early recognition and aggressive treatment with liposomal amphotericin B combined with surgical debridement are critical for survival, as delays in treatment result in devastating neurological outcomes. Read more 26 Feb 2026 - less than 1 minute read
This study reveals that myelin damage begins with swelling that can be reversible rather than immediate destruction, challenging the traditional view of demyelination as purely degenerative. Using live imaging in animal models and human MS tissue, researchers found that increased neuronal activity worsens myelin swelling while reduced activity is protective. Read more 25 Feb 2026 - less than 1 minute read
Updated meta-analysis of 10 RCTs shows general anesthesia during thrombectomy significantly improves revascularization rates compared to conscious sedation. When limited to trials using established stroke selection criteria, general anesthesia also improved functional independence at 90 days without increased mortality or hemorrhagic complications. Read more 24 Feb 2026 - less than 1 minute read
This systematic review of 124 studies (1210 patients) demonstrates that precise anatomical targeting in DBS for epilepsy significantly impacts outcomes, with ANT-DBS success correlating with proximity to the mammillothalamic tract junction. The analysis reveals substantial variability in current targeting approaches and provides quantitative evidence that electrode placement precision matters for seizure reduction. Read more 23 Feb 2026 - less than 1 minute read